A natural part of the cycle involves shedding around 50 to hairs per day. Each follicle produces hair for 2 to 6 years and then takes a break for several months. While the hair follicle is in its rest phase, the hair falls out. There are around , follicles on the scalp, but because each follicle rests at a different time and others produce hairs, hair loss is usually unnoticeable.
More noticeable hair loss occurs when there is a disruption to the growth and shedding cycle, or if the hair follicle is obliterated and replaced with scar tissue. Scientists now understand that pattern baldness occurs through a phenomenon known as miniaturization. DHT binds to receptors in the hair follicles and shrinks them, making them progressively smaller. Over time, the follicles produce thinner hairs, and they grow for a shorter time than normal.
Eventually, the follicle no longer produces hair, leaving the area bald. Currently, there are few available treatment options to halt or reverse miniaturization. Most hair loss treatments only manage hair loss, rather than being a permanent solution.
The only two drugs approved by the U. Minoxidil lotion is applied to the scalp and may work by increasing blood flow, and therefore nourishment, to the hair follicles. The treatment has zero effect on the hormonal process of hair loss, and its benefits are temporary. Hair loss continues if usage is discontinued. Finasteride inhibits type II 5-alpha-reductase, which is the enzyme responsible for converting testosterone into the more potent androgen DHT.
DHT levels are reported to be reduced by 60 percent when the drug is taken, which prevents the susceptible follicles from being affected by the hormone and returning their normal size.
Dutasteride Avodart is used to treat prostatic enlargement. While the FDA has not approved the drug to treat hair loss, physicians sometimes prescribe dutasteride off-label for male pattern baldness.
Dutasteride works similarly to finasteride, but it may be more effective. Like finasteride, dutasteride inhibits the activity of type II 5-alpha reductase. However, dutasteride additionally inhibits type I of the enzyme. Blocking both types of the enzyme lowers DHT even more and reduces the risk of damage to hair follicles.
This drug faces the same limitations as finasteride, meaning that it only works if taken daily and might become less effective over time. These therapies may slow down or prevent further hair loss, and they could stimulate regrowth from follicles that have been dormant but still viable. However, they can do little for follicles that have already become inactive. People are more likely to notice excessive hair loss. This is a good time to take action as it may be due to an underlying condition.
Symptoms of excessive hair loss include:. There are several possible reasons for excessive hair loss. One of the most common causes is due to genetics. Commercial products could help to slow and treat this type of balding. One example of these products is Rogaine. Pattern baldness occurs slowly with aging. Some more immediate causes of hair loss include:.
People looking for a treatment to help prevent or regrow hair have several potential options. The effectiveness of each option will vary from person to person. It is normal to experience some amount of hair thinning as people age. In other cases, there may be a medical cause. This article looks at the causes…. Female hair loss happens for many reasons, including natural aging. We cover treatments for hair loss, tips for hair growth, and ways to cope with….
Hair loss can be an upsetting condition to deal with. We look at the various causes, treatment options, and practical tips for preventing further loss. Hair loss is a side effect of certain medications. Read on to find out which medications can cause hair loss. We also provide tips on how to prevent…. Page last reviewed: 04 February Next review due: 04 February Hair loss.
Causes of hair loss It's normal to lose hair. Other types of hair loss may be temporary. They can be caused by: an illness stress cancer treatment weight loss iron deficiency Find out more about cancer and hair loss Non-urgent advice: See a GP if:. Karishma Tanna flaunts her decolletage in a pantsuit. Amy Winehouse's last dress sells for a whopping INR 1. Aishwarya Rai Bachchan's stylish looks from the noughties.
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