It may take several days, or even weeks, for some of your symptoms to start improving. Soon after you first start taking olanzapine, before your other symptoms improve, it may make you feel more relaxed and calm. Common side effects include: feeling sleepy, feeling dizzy, and constipation. It works by affecting the naturally occurring chemical messengers in your brain neurotransmitters , like dopamine and serotonin. Olanzapine can be taken by adults aged 18 years and over.
Dosage and strength Olanzapine tablets come in different strengths: 2. How to take olanzapine Take olanzapine once a day, at the same time each day. You can take it with or without food. How to take tablets Swallow your tablet whole with a drink of water. How to take tablets that dissolve in your mouth orodispersible Place the tablet on your tongue and let it dissolve. How to have injections Injections are given into the muscle of your buttock every 2 to 4 weeks by a doctor or nurse.
Will my dose go up or down? What if I forget to take it? Contact your doctor if you miss 2 or more doses. Do not take 2 doses at the same time to make up for a forgotten dose. What if I take too much? Taking too much olanzapine can lead to serious side effects. Urgent advice: Contact for advice now if:. You take more than your prescribed dose of olanzapine and: feel sleepy or tired have unusual body movements, especially face or tongue movements have problems standing and walking feel dizzy Call or visit You take more than your prescribed dose of olanzapine and: have a fast or irregular heartbeats have a seizure or fit start having problems with your speech have fast or slow breathing.
Common side effects These common side effects may affect up to 1 in 10 people. Tell your doctor if these side effects bother you or do not go away: feeling sleepy in the day putting on weight or an increase in your appetite feeling dizzy especially when getting up from a sitting or lying position rash constipation See your doctor if you have: sexual problems such as lower libido in men and women, or problems getting an erection — these can be signs of hormone changes problems with your movement infections including coughs, colds and chest infections, ear and eye infections, or urinary tract infections UTIs — these can be signs of a low white blood cell count Serious side effects Serious side effects are rare and happen in less than 1 in 1, people.
Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to olanzapine. Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. What to do about: feeling sleepy in the day — do not drive, cycle or use tools or machinery if you're feeling this way.
Do not drink alcohol as this will make you feel more tired. As your body gets used to olanzapine, these side effects should wear off. If they do not get better after a few weeks, speak to your doctor. Regular exercise will also help to keep your weight stable.
It should only last a few moments. As you get used to your medicine this problem should wear off. Ask your pharmacist which type is suitable for you to take while you are on olanzapine constipation — eat more high-fibre foods such as fresh fruit, vegetables and cereals. Try to drink several glasses of water or another non-alcoholic liquid every day.
If you can, it may also help to increase your exercise. Olanzapine and pregnancy Olanzapine can be taken during pregnancy and is not thought to be harmful to your baby. Do not stop taking your medicine unless your doctor tells you to. Olanzapine and breastfeeding If your doctor or health visitor says your baby is healthy, you can take olanzapine while breastfeeding.
Non-urgent advice: Tell your doctor if you're:. There are some medicines that may affect how olanzapine works. Important: Medicine safety Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. How does olanzapine work? How long does it take to work? How long will I take it for? This will depend on why you need olanzapine. How will olanzapine make me feel? You may find olanzapine makes you: able to concentrate better, and think more clearly able to get things done and stay focused remember things more easily feel more comfortable with other people and get along with them better more aware of what is real and what is not real stop hearing voices.
Can I take olanzapine for a long time? What will happen if I stop taking it? Withdrawal symptoms include: feeling or being sick sweating difficulty sleeping Talk to your doctor first if you want to go onto a lower dose or to stop taking olanzapine. How does it compare with other antipsychotic medicines?
How does olanzapine compare to lithium for bipolar disorder? Can olanzapine be used to treat anxiety? Can I drink alcohol with it? Will I gain or lose weight? Is there any food or drink I need to avoid? However, olanzapine can make you feel hungrier and put on weight. Will it affect my contraception?
Will it affect my fertility? Do not stop taking olanzapine without your doctor's advice. Olanzapine can pass into breast milk. If you are breastfeeding, tell your doctor if you notice severe drowsiness, irritability, feeding problems, tremors, or unusual muscle movements in the nursing baby.
The olanzapine orally disintegrating tablet Zyprexa Zydis may contain phenylalanine. Tell your doctor if you have phenylketonuria PKU. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
High doses or long-term use of olanzapine can cause a serious movement disorder that may not be reversible. The longer you use olanzapine, the more likely you are to develop this disorder, especially if you are a woman or an older adult.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Avoid driving or hazardous activity until you know how this medicine will affect you.
Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking olanzapine.
Use Zyprexa Olanzapine Injection exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. One common and possibly serious side effect of Zyprexa is significant weight gain, which has been reported as one of the top reasons people choose to stop taking the medication.
In addition, Zyprexa can increase blood sugar levels, putting a person at risk for developing diabetes. All three of these factors combined—weight gain, high blood sugar, and high cholesterol—can increase the patient's risk of heart disease, which is why it's important to review an exercise and nutritional plan with your doctor while on Zyprexa.
Other serious side effects of Zyprexa can include:. The FDA placed a black box warning on all antipsychotics atypical and typical due to this increased mortality risk. You'll want to share with your doctor of all the medications you take including prescription medication, herbals, vitamins, and any over-the-counter medications. Some medications interact with Zyprexa and may cause serious side effects or require that your doctor change your dose.
It's also important to give your doctor a complete medical history, including all your medical problems and allergies. For example, tell your doctor:.
Finally, when on Zyprexa, try and take it at the same time every day. If you accidentally forget a dose, take it as soon as you remember—unless it's almost time for the next dose anyway. Then skip it, and take your regular dose as scheduled.
Do not take two doses of Zyprexa at the same time. If you are unsure about your timing, call your doctor to be safe. Dealing with racing thoughts? Always feeling tired? Our guide offers strategies to help you or your loved one live better with bipolar disorder. Sign up for our newsletter and get it free.
Balancing benefits and harms of treatments for acute bipolar depression. J Affect Disord. National Library of Medicine, MedlinePlus. Updated June 15,
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